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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FLT1 All Species: 29.7
Human Site: T588 Identified Species: 65.33
UniProt: P17948 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17948 NP_001153392.1 1338 150769 T588 K F L Y R D V T W I L L R T V
Chimpanzee Pan troglodytes XP_509605 1338 150659 T588 K F L Y R D V T W I L L R T V
Rhesus Macaque Macaca mulatta XP_001117928 1481 165481 T731 K F L Y R D V T W I L L R T V
Dog Lupus familis XP_534520 1337 150703 T588 K F L Y R D I T W I L L R T V
Cat Felis silvestris
Mouse Mus musculus P35969 1333 149858 T589 K F L Y R D I T W I L L R T V
Rat Rattus norvegicus P53767 1336 150231 T588 K F L Y R D I T W I L L R T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519611 1329 147097 T588 K F L Y R D I T W I L L R T V
Chicken Gallus gallus Q8QHL3 1327 149408 P588 K D I S W I L P R T V T N Q T
Frog Xenopus laevis Q91909 954 106841 N263 S S N V F S Y N L T L K S D G
Zebra Danio Brachydanio rerio Q8AXB3 1302 146931 T591 K V P K D E T T L R I E P Y T
Tiger Blowfish Takifugu rubipres Q8AXC6 984 110714 S293 A E N E K G V S T Q S V W L D
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 88.2 89.9 N.A. 81.6 82.3 N.A. 71.9 68.9 25.6 44.1 28.7 N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.9 89.2 95.3 N.A. 90.3 90.7 N.A. 83.9 80.4 41.7 61.3 45.1 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 93.3 6.6 6.6 13.3 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 26.6 6.6 26.6 26.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 10 64 0 0 0 0 0 0 0 10 10 % D
% Glu: 0 10 0 10 0 10 0 0 0 0 0 10 0 0 0 % E
% Phe: 0 64 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 10 37 0 0 64 10 0 0 0 0 % I
% Lys: 82 0 0 10 10 0 0 0 0 0 0 10 0 0 0 % K
% Leu: 0 0 64 0 0 0 10 0 19 0 73 64 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 19 0 0 0 0 10 0 0 0 0 10 0 0 % N
% Pro: 0 0 10 0 0 0 0 10 0 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % Q
% Arg: 0 0 0 0 64 0 0 0 10 10 0 0 64 0 0 % R
% Ser: 10 10 0 10 0 10 0 10 0 0 10 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 10 73 10 19 0 10 0 64 19 % T
% Val: 0 10 0 10 0 0 37 0 0 0 10 10 0 0 64 % V
% Trp: 0 0 0 0 10 0 0 0 64 0 0 0 10 0 0 % W
% Tyr: 0 0 0 64 0 0 10 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _